An unsolvable murder. An aquatic doorway to nothingness. A wanderer at the end of time. And a cosmic train of planetary proportions. Four seemingly-unrelated events that will require the powers and insights of the members of the greatest Non-Team of them all, the original DEFENDERS, to connect the dots and challenge the strange power behind these disconnected happenings-before all of reality pays the price! Doctor Strange! The Immortal Hulk, Namor the Sub-Mariner! The Silver Surfer! Don´t call them a team-all them the DEENDERS!