Don Roberto Luciano, boss of the Sicilian Mafia, agrees to be chief witness in the trial of Paul Carolla, who murdered Luciano´s firstborn son, Michael, 20 years ago. Despite round-the-clock protection, all the Luciano men are killed the night before a family wedding.
The don´s wife, Graziella, holds together what´s left of the family - daughters-in-law Theresa and Sophia, and Theresa´s daughter Rosa - while instructing their lawyer to sell off business holdings.
Eventually the women become involved in the business themselves, trying to recover money that´s disappeared into Carolla´s hands. Following a courtroom shootout, Carolla´s adopted son Luka, using his knowledge of organization politics and his mastery of murder, becomes the women´s partner and protector.
Once the Luciano women discover Luka´s secret, however, they implacably take revenge in the ruthless manner of their age-old code, and the strongest of them becomes the new head of the family, the bella mafiosa . . .